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2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
CAS No. ——
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) ( —— )
产品货号. M30077 CAS No. ——
2-Furoyl-LIGRLO-amide is a potent and selective protease-activated receptor 2 (PAR2) agonist.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述2-Furoyl-LIGRLO-amide is a potent and selective protease-activated receptor 2 (PAR2) agonist.
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产品描述2-Furoyl-LIGRLO-amide is a potent and selective protease-activated receptor 2 (PAR2) agonist.(In Vitro):2-Furoyl-LIGRLO-amide (2-Furoyl-LIGRLO-NH2) is equally effective to and 10 to 25 times more potent than SLIGRLNH2 for increasing intracellular calcium in cultured human and rat PAR2-expressing cells, respectively. In bioassays of tissue PAR2 activity, measured as arterial vasodilation and hyperpolarization, 2-Furoyl-LIGRLO-amide (2-Furoyl-LIGRLO-NH2) is 10 to 300 times more potent than SLIGRL-NH2. Unlike trans-cinnamoyl-LIGRLO-NH2, 2-Furoyl-LIGRLO-amide do not cause a prominent non-PAR2-mediated contraction of murine femoral arteries.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Proteise-activated receptor 2 (PAR2)
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量——
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称Sequence:{Fur-2-oyl}-Leu-Ile-Gly-Arg-Leu-{Orn}-NH2
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
McGuire JJ, et al. 2-furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist. J Pharmacol Exp Ther. 2004 Jun;309(3):1124-31.
产品手册
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