2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

2-Furoyl-LIGRLO-amide is a potent and selective protease-activated receptor 2 (PAR2) agonist.

2-Furoyl-LIGRLO-amide is a potent and selective protease-activated receptor 2 (PAR2) agonist.(In Vitro):2-Furoyl-LIGRLO-amide (2-Furoyl-LIGRLO-NH2) is equally effective to and 10 to 25 times more potent than SLIGRLNH2 for increasing intracellular calcium in cultured human and rat PAR2-expressing cells, respectively. In bioassays of tissue PAR2 activity, measured as arterial vasodilation and hyperpolarization, 2-Furoyl-LIGRLO-amide (2-Furoyl-LIGRLO-NH2) is 10 to 300 times more potent than SLIGRL-NH2. Unlike trans-cinnamoyl-LIGRLO-NH2, 2-Furoyl-LIGRLO-amide do not cause a prominent non-PAR2-mediated contraction of murine femoral arteries.

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Others

Other Targets

Proteise-activated receptor 2 (PAR2)

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>98% (HPLC)

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Sequence:{Fur-2-oyl}-Leu-Ile-Gly-Arg-Leu-{Orn}-NH2

(-20℃)

With Ice Pack

≥ 2 years